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Slow drug uptake in the brain (the "first-pass effect") is a key component of the pharmacokinetic-pharmacodynamic (PK-PD) relationship. A PK-PD relationship is the basis for a full PK-PD profile; indeed, this profile and its interpretation provide the therapeutic rationale. In most circumstances, slow drug uptake in the brain has important consequences for the concentration of drug in other tissues, and for clinical effect. In these cases, the PK-PD relationship will be more complex than that implied by a simple linear relationship. A graphic method is used to illustrate this concept.Q:
How to prevent an Event Handler from getting called recursively
I am trying to prevent an event handler from being called recursively. I saw someone using the following code to achieve this:
if (e.Handled)
return;
if (e.OriginalSource is WidgetEventArgs)
{
e.Handled = true; ac619d1d87
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